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CPAP trumps MAD in certain parameters, study finds

CPAP trumps MAD in certain parameters, study finds

YARMOUTH, Maine – Treatment with CPAP devices was better than mandibular advancement devices at normalizing polysomnographic parameters and improving quality of life in patients with mild obstructive sleep apnea, according to a recent study published in Sleep Breathing Physiology and Disorders. Fatigue was improved in both CPAP and MAD groups, and daytime sleepiness, mood and sustained attention showed no difference. This study was a single-blind, parallel, randomized clinical trial with controls. The sample was composed of individuals between 18 and 65 years of age with a body mass index of < 35 kg/m2 and apnea/hypopnea index above five and less than 15. Participants were submitted to physical examination, polysomnography, and the following questionnaires: Pittsburgh Sleep Quality Index, Berlin Questionnaire, Epworth Sleepiness Scale, Stanford Sleepiness Scale, Karolinska Sleepiness Scale, Modified Fatigue Impact Scale, Functional Outcomes of Sleep Questionnaire, Beck Anxiety Inventory, and Beck Depression Inventory. They were also presented with the following tests: maintenance of wakefulness test and psychomotor vigilance task. Of 79 patients, 25 were in the MAD group, 31 in the CPAP group, and 23 in the control group. 

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