Elevated glucose raises dementia risk

Thursday, August 31, 2006

SAN FRANCISCO - Chronically elevated blood sugar levels can impair cognitive function in older women, researchers at the University of California-San Francisco say. Postmenopausal women with HbA1c levels of 7% or higher had four times the risk of mild impairment or dementia over four years compared with women whose HbA1c was lower than 7%. The investigators conducted a four-year prospective study of 1,983 postmenopausal women with osteoporosis who had HbA1c levels measured at baseline. The women, 53 of whom were known to be diabetic at baseline, had a mean age of 67.2 years. The study found that for every 1% increase in HbA1c, women had a greater age-adjusted likelihood of developing mild impairment or dementia.